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The Neuroscience Division conducts innovative research in the field of basic and applied neurosciences. Our research integrates a variety of modalities including molecular, behavioural, and clinical neuroscience, as well as ageing, genetics and brain imaging. The Division is also involved in research training of highly qualified personnel, translational research, drug discovery, and knowledge translation and dissemination. In addition, the members of this division are involved in academic teaching activities at the undergraduate, graduate and post-graduate levels at McMaster University. The members of this Division, in cooperation and collaboration with other Divisions of the Department, McMaster, and the international research community, generate basic science knowledge applicable to clinical settings. The primary goal is to further our understanding of fundamental mechanisms implicated in mental, behavioural, and neurological disorders, through the development of novel biomarkers, novel drugs and drug carriers, and pre-clinical animal models using a fully translational approach. This knowledge is then translated back to the clinical setting with the goal of improving the diagnosis, treatment, and/or prevention of mental, behavioural and neurological illnesses.  


  • Understanding the fundamental mechanisms involved in mental and neurological disorders
  • Development of biomarkers for early diagnosis and therapeutic implications
  • Investigation of new pre-clinical models for psychiatric disorders
  • Development of new drug formulations for efficient drug delivery to central nervous system
  • Improve diagnosis, treatment, and/or prevention of mental, behavioural and neurological diseases


Application to Consumer

Faculty members and students enrolled in the Neuroscience program are integrated into teaching and research activities at McMaster University. They are involved in various undergraduate, graduate and post-graduate programs.

Other Faculty

  • Ram Mishra, PhD
    • Molecular mechanisms involved in pathogenesis of schizophrenia and Parkinson’s disease; drug development for the treatment of mental and neurological illnesses; blood test for the early diagnosis of neurodegenerative diseases.
  • Henry Szechtman, PhD.
    • Mechanism and functional role of drug sensitization, animal models of OCD, brain mechanisms of schizophrenia
  • Margaret Fahnestock, PhD.
    • Synthesis and regulation of neurotophic factors with special regard to CNS disorders
  • Lennard Niles, PhD.
    • Cellular and molecular neuroendrocrinology and neuropharmacology, with relevance to brain function and behaviour
  • Todd Hoare, PhD.
    • Design and synthesis of novel materials for biomedical and environmental applications
  • Benecio Frey, MD PhD.
    • Cerebral mechanisms involved in the neurobiology of bipolar and major depressive disorder, with emphasis in female-reproductive life events
  • Robert Zipursky, MD
    • Optimizing treatment response and outcomes in schizophrenia
  • James MacKillop, PhD
    • Behavioral economics and neuroeconomics to understand alcoholism, nicotine dependence, and other forms of addiction.

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