Peter Boris Centre for Addictions Research
The Peter Boris Centre for Addictions Research conducts state-of-the-art research on addictive disorders. These disorders are broadly defined, including alcoholism, nicotine dependence, and other substance use disorders, but also problem gambling and compulsive eating. Using a translational framework, the Centre has four principal foci: 1) behavioral research investigating in vivo determinants of addictive behavior; 2) neuroimaging research investigating the neural determinants of addiction-related motivation); 3) clinical research investigating novel treatments, predictors of treatment response, and mechanisms of action; and 4) genetic research investigating the role of genetic variation in behavioral performance, neural activity, and clinical outcomes. Studies typically integrate the preceding domains, with the goal of conducting controlled experimental research that nonetheless addresses important clinical questions. Similarly, the Centre has partnered with clinical programs at St. Joseph’s Healthcare Hamilton, McMaster University, and Homewood Health Centre to develop research systems that mutually enhance both research and clinical care.