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Bio

Dr. Patricia Rosebush teaches in the undergraduate programme at McMaster Medical School, and in the Psychiatry Residency Programme.  In the medical school she was the psychiatry sub-unit planner for the Brain and Behaviour courses until 2005.  With neurologist Dr. Michael Mazurek she has developed courses in neuropsychiatry, for both undergraduates and graduates.  These reflect their collaborative clinical and research work and have been presented as courses at the APA in 1998, 1999, and 2000 as part of the McMaster Muskoka Seminar Series from 1999 to 2006.

Education

  • FRCP(C)
  • M.D., McMaster University
  • M.Sc.N., University of Toronto

Research Areas

Dr. Rosebush has been invited to present her research locally, nationally and internationally and she has developed a number of important clinical data sets which include:

A prospective study of first onset psychosis from 1988 to 2005:  Dr. Rosebush has treated and studied the efficacy and side-effect profiles of various antipsychotic agents in over 500 first-onset psychosis patients.  This work has been supported by OMHF and The Stanley Foundation.

Dr. Rosebush has been invited to present her research locally, nationally and internationally and she has developed a number of important clinical data sets which include:

A prospective study of first onset psychosis from 1988 to 2005:  Dr. Rosebush has treated and studied the efficacy and side-effect profiles of various antipsychotic agents in over 500 first-onset psychosis patients.  This work has been supported by OMHF and The Stanley Foundation.

Neuroleptic malignant syndrome (NMS):  Dr. Rosebush has personally treated and studied the largest series of such patients in the world.  This has led to recommendations for treatment, elucidation of the biochemical profile and insight into the underlying pathophysiology.

Catatonia: To date, Dr. Rosebush has prospectively treated and followed over 150 patients with catatonia and has published widely on the efficacy of benzodiazepines in both acute and chronic catatonia states. 

Late-onset delusional disorder: Dr. Rosebush has prospectively treated and followed a large cohort of patients with this condition from the time of their first presentation. Stability of diagnosis, response to treatment, medication side effect, concurrent mood symptoms profile, underlying medical/neurological illnesses, prognosis and outcome are addressed.

Conversion disorder:  Since 1990 Dr. Rosebush has developed expertise in the diagnosis and treatment of this serious somatoform disorder in children, adolescents and adults.  She is nationally and internationally recognized for her work in the field and receives referrals from across the country.

The neuropsychiatry of inherited metabolic disorders such as adult-onset Tay Sachs disease, metachromatic leukodystrophy and adrenoleukodystrophy.

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